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PHA induced blastoid transformation of lymphocytes in leprosy contacts
Leprosy in India
|April 1, 1982
Abstract:
PHA-induced blastoid transformation of lymphocytes was studied in 29 contacts of leprosy patients. 21 contacts taking DDS as prophylaxis showed significant depression of lymphocyte transformation while 8 contacts not taking DDS showed no depression as compared to controls. DDS thus has an inhibitory effect on cell mediated immune response.