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Nerve damage in tuberculoid leprosy

P K Reddy, N Prabhudass

    Leprosy in India
    |April 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Borderline Tuberculoid leprosy commonly causes sensory and autonomic deficits in the ulnar nerve areas. However, motor function in these areas is often spared in some patients, suggesting a selective nerve damage mechanism.

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    Area of Science:

    • Neurology
    • Infectious Diseases
    • Dermatology

    Background:

    • Leprosy, particularly Borderline Tuberculoid leprosy, is known to affect peripheral nerves.
    • The ulnar nerve is frequently involved, leading to potential sensory and motor impairments in the hand.

    Purpose of the Study:

    • To investigate the pattern of ulnar nerve damage in patients with Borderline Tuberculoid leprosy.
    • To determine the prevalence of sensory, autonomic, and motor deficits in the ulnar nerve distribution.

    Main Methods:

    • A study involving forty-five patients diagnosed with Borderline Tuberculoid leprosy.
    • Comprehensive sensory and voluntary muscle testing of the hands was performed on all participants.

    Main Results:

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  • All patients exhibited sensory and autonomic deficits in areas supplied by the ulnar nerve.
  • Motor deficits were observed in forty out of forty-five patients, indicating selective sparing in five cases.

    • Conclusions:

    • Borderline Tuberculoid leprosy predominantly impacts sensory and autonomic functions of the ulnar nerve.
    • The study highlights a potential mechanism for selective sparing of motor function in a subset of patients, warranting further investigation.