Related Experiment Video
Updated: Aug 18, 2026

Knee Arthrocentesis in Adults
Published on: February 25, 2022
Septic arthritis caused by Pasteurella multocida
Abstract:
A patient with rheumatoid arthritis developed an infection in the right hand after she administered an antibiotic capsule to her cat. Two weeks after this, septic arthritis developed in her right knee. The organism isolated was Pasteurella multocida, which is part of the feline normal oral flora. The infection was treated with penicillin and drainage.
Insights
A rheumatoid arthritis patient developed septic arthritis in her knee after a Pasteurella multocida hand infection from her cat. Prompt treatment with antibiotics and drainage resolved the infection.
Area of Science:
- Infectious Diseases
- Rheumatology
- Microbiology
Background:
- Rheumatoid arthritis (RA) is a chronic autoimmune disease primarily affecting joints.
- Patients with autoimmune conditions may have altered susceptibility to infections.
- Feline oral flora harbors various bacteria, including potential human pathogens.
Observation:
- A patient with rheumatoid arthritis experienced a hand infection after administering medication to her cat.
- The hand infection subsequently led to septic arthritis in the ipsilateral knee.
- Pasteurella multocida, a common bacterium in cat saliva, was identified as the causative agent.
Findings:
- Pasteurella multocida, part of normal feline oral flora, can cause opportunistic human infections.
- Septic arthritis is a serious joint infection that can arise from bloodstream seeding or direct inoculation.
- The patient's infection was successfully treated with penicillin and surgical drainage.
Implications:
- Highlights the zoonotic potential of Pasteurella multocida, particularly from companion animals.
- Emphasizes the importance of wound care and infection prevention in immunocompromised individuals.
- Underscores the need for prompt diagnosis and management of septic arthritis to prevent joint damage.
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