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Updated: Aug 9, 2026

Rapid Analysis of Chromosome Aberrations in Mouse B Lymphocytes by PNA-FISH
Published on: August 19, 2014
Chromosome aberration persisting in cells of continuously irradiated mice
Abstract:
Cytogenetical analysis of the bone marrow cells in mice irradiated continuously with the dose rate 0.478 Gy/day made within the course of various accumulated doses demonstrated the decrease in the number of chromosome aberrations till the post irradiation day 3 in all groups reaching about 75% on average. At further examination periods on day 10 and 30 the decrease in the aberrations appeared to be slower and was dependent on the magnitude of the accumulated dose. Increased number of the aberrant cells as compared with the controls was noted in the groups with the accumulated dose higher than 10 Gy and on the hundred postirradiation day, as well.
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