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Updated: Oct 9, 2026

Simultaneous Intracellular Recording of a Lumbar Motoneuron and the Force Produced by its Motor Unit in the Adult Mouse In vivo
Published on: December 5, 2012
Acetylcholinesterase content in both motor nerve and muscle is correlated with twitch properties
Abstract:
The activity and molecular forms of acetylcholinesterase (AChE) were studied in the rat soleus muscle and its nerve, as compared to their fast-twitch counterparts. The soleus muscle and its nerve exhibited both significantly lower AChE activity and less of the G4 (10S) molecular form. In addition, the soleus muscle displayed a specific increase in the A8 (13S) and A4 (8.8S) asymmetric forms, not seen in any of the fast-twitch muscles examined. These results indicate that the AChE content of a muscle and its nerve are linked and depend on the twitch properties, and that the slow-twitch muscle is characterized by a specific set of AChE molecular forms.
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