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Group G streptococcal arthritis

A Bradlow, R G Mitchell, A G Mowat

    Rheumatology and Rehabilitation
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Lancefield Group G streptococcus is an uncommon cause of septic arthritis, often seen in patients with underlying conditions like rheumatoid arthritis or cancer. Prompt antibiotic treatment with penicillin or erythromycin is generally effective.

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    Area of Science:

    • Clinical microbiology and infectious diseases.
    • Rheumatology and immunology.
    • Oncology and internal medicine.

    Background:

    • Septic arthritis is a serious joint infection requiring prompt diagnosis and treatment.
    • Lancefield Group G streptococcus is a less common bacterial cause of bloodstream and soft tissue infections.
    • Understanding the clinical spectrum and risk factors for rare pathogens is crucial for effective patient management.

    Observation:

    • Six cases of Lancefield Group G streptococcal septic arthritis were identified.
    • Pre-existing chronic arthritis (including rheumatoid arthritis) and joint prosthesis infection were noted in two patients.
    • Neoplastic disease was present in three patients, either preceding or concurrent with septic arthritis.
    • Prominent skin manifestations, such as cellulitis and scarlatiniform rash, occurred in five cases.

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  • A potential zoonotic transmission from a pet dog was observed in one instance.
  • The unusual association of Group G streptococcus with specific patient populations and clinical presentations is highlighted.
  • Findings:

    • Five patients achieved a favorable response to penicillin therapy.
    • One patient, allergic to penicillin, was successfully treated with erythromycin.
    • The study demonstrates the efficacy of standard antibiotic regimens for this specific pathogen.
    • The increasing recognition of Group G streptococcal arthritis in the United Kingdom is noted.

    Implications:

    • Clinicians should consider Lancefield Group G streptococcus in the differential diagnosis of septic arthritis, particularly in immunocompromised individuals or those with chronic joint disease.
    • Early recognition and appropriate antibiotic selection are key to favorable outcomes.
    • Further surveillance may be warranted to understand the epidemiology and clinical significance of this emerging infectious cause of arthritis.