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[Boletus luridus and alcohol. Case report]
Schweizerische Medizinische Wochenschrift
|August 21, 1982
Summary
Certain mushrooms, like Boletus luridus, can cause a disulfiram-alcohol reaction when consumed with alcohol. This study describes three cases of mild reactions, noting the unknown toxin in Boletus luridus.
Area of Science:
- Toxicology
- Mycology
- Pharmacology
Background:
- Certain substances, including specific drugs (e.g., cephalosporins, metronidazole), calcium cyanamide, and some mushrooms, can induce a disulfiram-alcohol reaction when ingested with ethanol.
- This reaction is characterized by symptoms similar to those experienced when combining alcohol with the medication disulfiram.
Observation:
- This report details three distinct cases of individuals experiencing a disulfiram-alcohol type reaction.
- The common factor in these cases was the co-ingestion of Boletus luridus mushrooms and alcohol.
Findings:
- The observed reactions in the described cases were generally mild and did not lead to severe symptoms.
- Unlike the known mechanism in Coprinus atramentarius, the specific toxic compound responsible for the disulfiram-alcohol reaction in Boletus luridus remains unidentified.
Implications:
- The findings highlight Boletus luridus as another mushroom capable of causing alcohol-interaction toxicity.
- Further research is warranted to identify the specific toxin in Boletus luridus responsible for this reaction.
- Awareness among healthcare providers and the public regarding potential mushroom-alcohol interactions is crucial for preventing adverse events.