Bowen's disease at the limbus

Ten cases of Bowen's disease at the limbus have been clinicopathologically studied and followed up for 1 1/2 to 9 years. The clinical appearance might be classified into 3 principal forms; i.e., papillomatous, leukoplakic and gelatinous forms. However, histopathological differences could not be detected in the respective forms. In the follow-up study no recurrence was observed in the 8 cases treated with excision and cryotherapy, though recurrence and malignant change took place in one case of the remaining 2 cases, treated with excision only.