Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Resorbable implant for orbital defects

E L Chuang, R E Bensinger

    American Journal of Ophthalmology
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Tricalcium phosphate ceramic effectively replaced by new bone tissue in rabbit orbital defects over 40 weeks. This synthetic bone substitute shows excellent integration without adverse reactions.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Virological, clinical, and ophthalmologic features of cytomegalovirus retinitis after hematopoietic stem cell transplantation.

    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2001
    Same author

    New classification of peripheral retinal vascular changes in sickle cell disease.

    The British journal of ophthalmology·1994
    Same author

    Peripheral retinal vasculature in normal Jamaican children.

    The British journal of ophthalmology·1994
    Same author

    Management of retinal detachment associated with CMV retinitis in AIDS patients.

    Eye (London, England)·1992
    Same author

    Treatment of iatrogenic choriovitreal neovascularisation in sickle cell disease.

    The British journal of ophthalmology·1991
    Same author

    Detection of herpesvirus DNA in vitreous and aqueous specimens by the polymerase chain reaction.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1991
    Same journal

    Clinical Utility of Ultra-Widefield Swept-Source OCT for Intraocular Tumors: Comparison With Ultrasonography, SD-OCT, and MRI.

    American journal of ophthalmology·2026
    Same journal

    Therapeutic Advances in Corneal Scar management: Topical Treatments, Mesenchymal Cell Therapy and Stromal Transplantation.

    American journal of ophthalmology·2026
    Same journal

    Increased Risk for Ocular Surface Neoplasia in Recipients of Solid Organ Transplant.

    American journal of ophthalmology·2026
    Same journal

    Aflibercept With vs Without Reduced-Fluence Photodynamic Therapy for Polypoidal Choroidal Vasculopathy: Optical Coherence Tomography Angiographic changes from a randomized clinical trial.

    American journal of ophthalmology·2026
    Same journal

    Posterior Segment Risk Factors for Penetrating Keratoplasty Failure.

    American journal of ophthalmology·2026
    Same journal

    Rates, Timing, and Predictors of Retreatment Across Risk-Cohorts in Retinopathy of Prematurity: Intravitreal Bevacizumab Injection vs Laser.

    American journal of ophthalmology·2026
    See all related articles

    Area of Science:

    • Biomaterials Science
    • Orthopedic Research
    • Craniofacial Surgery

    Background:

    • Synthetic bone substitutes are crucial for bone defect repair.
    • Tricalcium phosphate ceramic is a promising biomaterial for bone regeneration.
    • Evaluating its efficacy in orbital reconstruction is essential.

    Purpose of the Study:

    • To assess the bone healing potential of tricalcium phosphate ceramic.
    • To evaluate the integration and resorption of tricalcium phosphate ceramic in orbital defects.
    • To determine the long-term biocompatibility of this synthetic bone substitute.

    Main Methods:

    • Surgical creation of defects in rabbit inferior orbital rims.
    • Implantation of tricalcium phosphate ceramic into the defects.

    Related Experiment Videos

  • Histological analysis at 3, 8, 24, and 40 weeks post-implantation.

    • Main Results:

    • Early fibrous encapsulation and ingrowth observed.
    • Osteoid formation and partial implant resorption noted by 8 weeks.
    • Progressive replacement with new trabecular bone by 24 and 40 weeks.
    • No signs of infection, migration, or rejection were detected.

    Conclusions:

    • Tricalcium phosphate ceramic demonstrates excellent osteoconductivity and biocompatibility.
    • It serves as an effective scaffold for bone regeneration in orbital defects.
    • This synthetic bone substitute is a viable option for craniofacial reconstruction.