Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Indwelling chemical sensors based on semiconductor technology

R C Eberhart, T H Thomasson, M S Munro

    Critical Care Medicine
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A simple radioassay for detection of antithyroglobulin autoantibodies.

    The Indian journal of medical research·1992
    Same author

    An immunoradiometric assay for measurement of serum thyroglobulin.

    The Indian journal of medical research·1992
    Same author

    Modification of radiosensitivity by the so-called tissue recovery stimulator. I. Radiosensitizing effects of solcoseryl.

    Journal of radiation research·1992
    Same author

    Postnatal laminar development of cholinergic receptors, protein kinase C and dihydropyridine-sensitive calcium antagonist binding in rat visual cortex. Effect of visual deprivation.

    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience·1992
    Same author

    Cerebral glucose metabolic rates after 30 and 45 minute acquisitions: a comparative study.

    Journal of nuclear medicine : official publication, Society of Nuclear Medicine·1992
    Same author

    Resolution of dihydroxyeicosanoates and of dihydroxyeicosatrienoates by chiral phase chromatography.

    Analytical biochemistry·1992

    New chemical sensors, similar to computer transistors, can continuously monitor serum electrolytes like hydrogen ion and CO2. These miniaturized, inexpensive chips show promise for critical care patient monitoring.

    Area of Science:

    • Biomedical Engineering
    • Chemical Sensing
    • Microelectronic Devices

    Background:

    • Field-effect transistors (FETs) are fundamental to computing.
    • Continuous monitoring of physiological parameters is crucial in critical care.

    Purpose of the Study:

    • To develop indwelling chemical sensors for continuous monitoring of serum electrolytes.
    • To explore the potential of FET-based sensors for patient monitoring in critical care.

    Main Methods:

    • Utilizing ion-filtering membranes with FET-like chemical sensors.
    • Employing semiconductor processing for miniaturized, multi-ion sensor chips.
    • Incorporating chip-based signal processing for stability and temperature compensation.

    Main Results:

    Related Experiment Videos

    • Demonstrated continuous measurement of hydrogen ion and CO2 tension.
    • Developed miniaturized sensor chips with potential for cost-effective production.
    • Addressed challenges in sensor stability, blood compatibility, and reference electrode design.

    Conclusions:

    • FET-based chemical sensors offer a promising, inexpensive solution for continuous patient monitoring in critical care.
    • Further development is needed to overcome stability and biocompatibility issues.
    • Preliminary in vitro and in vivo performance is encouraging for future applications.