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Related Experiment Videos

The normal right ventricular response to supine exercise

D Morrison, S Sorensen, J Caldwell

    Chest
    |December 1, 1982
    PubMed
    Summary

    Right ventricular ejection fraction (RVEF) increases with exercise in healthy males. RV systolic function is afterload-dependent, influenced by total pulmonary resistance and heart rate.

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    Area of Science:

    • Cardiovascular Physiology
    • Exercise Physiology
    • Nuclear Cardiology

    Background:

    • Assessing right ventricular (RV) systolic function during exercise is crucial for understanding cardiovascular adaptation.
    • Radionuclide angiography provides a non-invasive method to evaluate RV ejection fraction (RVEF) and stroke counts.

    Purpose of the Study:

    • To investigate the relationship between right ventricular systolic function and hemodynamic parameters during graded maximal supine bicycle exercise in healthy young males.
    • To determine if RV systolic function is afterload-dependent and identify potential afterload indices.

    Main Methods:

    • Nine healthy young males underwent graded maximal supine bicycle exercise.
    • Hemodynamic parameters and gated blood pool scans (radionuclide angiography) were monitored at rest and during exercise.

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  • Multivariate analysis was used to assess the relationship between RVEF and pulmonary artery pressure, total pulmonary resistance, and heart rate.

    • Main Results:

    • RVEF increased significantly with maximal exercise in all subjects.
    • A close correlation was observed between RV and left ventricular (LV) stroke counts.
    • RVEF was inversely related to total pulmonary resistance and positively related to heart rate, indicating afterload dependency.

    Conclusions:

    • Right ventricular systolic function in normal subjects is afterload-dependent.
    • Total pulmonary resistance may serve as a suitable index for RV afterload during exercise.
    • Heart rate is an important factor to consider when interpreting changes in RVEF.