[Ultrastructural changes in the liver and leukocytes of a child with Niemann-Pick disease]

Morphological findings in Niemann-Pick disease of an infant are described. By electron microscopy in the cytoplasma of leukocytes and hepatocytes mostly moderaty electrodense unmature lipid-containing cytosomes were seen. Morphological alterations found in the leukocytes and hepatocytes in contrast to the earlier findings appeared to be similar. Authors stress the importance of electron microscopic investigation of peripheric leukocytes.