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Updated: Aug 14, 2026

Local Application of Drugs to Study Nicotinic Acetylcholine Receptor Function in Mouse Brain Slices
Published on: October 29, 2012
[Further study and the comparative characteristics of potential stimulants of higher nervous activity]
Abstract:
The most active stimulants of the higher nervous activity (nootropil, tonibral, mefexamide, sydnocarb, pyrroxane, ethimizole, gutimin and analogs) were studied and compared as regards their effects on the time course of forming the conditioned reflex of avoidance in rats during one-time and "fraction" learning. The models of special retraining were used to examine the drug effects on the phases of consolidation and the time course of the reflex reproduction. The most active compounds have been defined in terms of the parameters under consideration.
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