An analytical method for simple N-nitrosamides

A clean-up method is described which sufficiently removes interfering chemicals from feces so that the colorimetric procedure of Preussmann & Schaper-Druckrey (1972), or HPLC with UV detection, can be used reliably to detect N-nitrosamides. The method has given reasonably good recoveries of four different N-nitrosamides intentionally added to feces. The method, or parts of it, should be applicable to the clean-up of other complex samples, such as food, biological tissues and body fluids.