Polypeptide antigens of the synaptic plasma membranes of the rat brain

Antisera to two groups of polypeptides isolated from central nervous system synaptic plasma membranes of mature rats, were used to study antigenic polypeptides of new born and adult rats. Immunoprecipitation and acrylamide gel electrophoretic analysis demonstrated greater amounts of antigenic polypeptides in adult rats. These antigenic polypeptides may be involved in synaptogenesis.