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Cancer in patients with psoriasis
Journal of the American Academy of Dermatology
|November 1, 1982
Summary
Patients with psoriasis have a significantly higher incidence of skin cancer compared to those with diabetes. However, internal cancer prevalence was not significantly different between the two groups.
Area of Science:
- Dermatology
- Oncology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- The relationship between psoriasis and cancer risk requires further investigation.
Purpose of the Study:
- To compare the incidence of skin and internal cancers in patients with psoriasis versus patients with diabetes.
Main Methods:
- A study involving 150 non-PUVA-treated patients with psoriasis.
- Comparison with a control group of patients with diabetes.
- Statistical analysis of cancer incidence and prevalence.
Main Results:
- Skin cancer incidence was 1.96/yr in the psoriasis group, three times higher than in the diabetes group (statistically significant).
- Internal cancer prevalence was half that of the diabetes group, but this difference was not statistically significant.
Conclusions:
- Psoriasis patients exhibit a significantly elevated risk of developing skin cancer.
- The study did not find a significant difference in internal cancer prevalence between psoriasis and diabetes patients.