Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cingulate cortex: its role in Pavlovian conditioning

S L Buchanan, D A Powell

    Journal of Comparative and Physiological Psychology
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Regional localization of [(14)C]mescaline in rabbit brain after intraventricular administration : Effects of chlorpromazine and iproniazid pretreatment.

    Neurochemical research·2013
    Same author

    The Interrelation of Physician and Surgeon in Regard to Non-Pulmonary Tuberculosis.

    British medical journal·2010
    Same author

    Where does foodborne illness happen-in the home, at foodservice, or elsewhere-and does it matter?

    Foodborne pathogens and disease·2009
    Same author

    Encoding and retrieval are differentially processed by the anterior cingulate and prelimbic cortices: a study based on trace eyeblink conditioning in the rabbit.

    Neurobiology of learning and memory·2009
    Same author

    Prefrontal control of trace eyeblink conditioning in rabbits: role in retrieval of the CR?

    Behavioral neuroscience·2008
    Same author

    Discriminative delay Pavlovian eyeblink conditioning in veterans with and without posttraumatic stress disorder.

    Journal of anxiety disorders·2007
    Same journal

    Conditioned responses in young puppies.

    Journal of comparative and physiological psychology·2014
    Same journal

    The effects of glutamic acid on the behavior of the white rat.

    Journal of comparative and physiological psychology·2010
    Same journal

    Prediction and automatic control of alertness; control of look-out alertness.

    Journal of comparative and physiological psychology·2010
    Same journal

    Electroconvulsive shock in rats under ether anesthesia.

    Journal of comparative and physiological psychology·2010
    Same journal

    Simple reaction chains and their integration; heterogeneous chaining with terminal reinforcement.

    Journal of comparative and physiological psychology·2010
    Same journal

    Left-right tendency in the hermit crab, Clibinarius zebra Dana.

    Journal of comparative and physiological psychology·2010
    See all related articles

    Anterior cingulate cortex lesions in rabbits altered conditioned heart rate responses during Pavlovian conditioning. This brain region is crucial for processing cardiovascular responses to stimuli.

    Area of Science:

    • Neuroscience
    • Behavioral Neuroscience
    • Cardiovascular Physiology

    Background:

    • The cingulate cortex plays a role in learning and memory.
    • Understanding the specific functions of anterior and posterior cingulate cortex is essential for elucidating neural mechanisms of conditioning.

    Purpose of the Study:

    • To investigate the differential roles of anterior and posterior cingulate cortex in Pavlovian conditioning in rabbits.
    • To examine the effects of cingulate cortex lesions and stimulation on cardiovascular responses during conditioning.

    Main Methods:

    • New Zealand albino rabbits underwent lesioning or sham surgery targeting anterior or posterior cingulate cortex.
    • Pavlovian conditioning procedures used auditory tones as conditioned stimuli and paraorbital electric shock as the unconditioned stimulus.

    Related Experiment Videos

  • Cardiovascular parameters (heart rate, blood pressure) and somatomotor responses were monitored. Electrical stimulation of the cingulate cortex was also performed.

    • Main Results:

    • Anterior cingulate lesions attenuated conditioned heart rate decelerations but enhanced the bradycardiac component of the orienting reflex.
    • Posterior cingulate lesions enhanced the bradycardiac component of the conditioned response, particularly later in training.
    • Electrical stimulation of the anterior cingulate cortex elicited significant heart rate decelerations, mediated by cholinergic pathways.

    Conclusions:

    • The anterior and posterior cingulate cortices have distinct roles in mediating cardiovascular responses during Pavlovian conditioning.
    • The anterior cingulate cortex is involved in processing the cardiovascular component of stimulus-elicited responses.
    • Findings contribute to understanding the neural basis of associative learning and autonomic regulation.