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[Patterns of the changes in the chromatin proteins of rabbit and human brain in ontogeny]
Abstract:
The fractional composition of chromatin proteins of various morphological structures and areas in the rabbit and human brain was studied by means of electrophoresis in polyacrylamide gel with sodium dodecyl sulphate at different stages of pre- and postnatal ontogenesis. Both the species are characterized by differences in the set of chromatin proteins between different brain structures (regional heterogeneity) arising and increasing during ontogenesis. The heterochronism was found in the appearance of a number of high molecular weight fractions of chromatin proteins suggesting the advanced development of genetic apparatus of the phylogenetically ancient brain structures. The human brain, unlike the rabbit one, is characterized by individual differences augmenting during ontogenesis.