Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Time-dependent recovery from electroconvulsive shock-induced amnesia

H D Day, Y K Han

    Physiology & Behavior
    |August 1, 1982
    PubMed
    Summary

    Electroconvulsive shock (ECS) impairs memory, but recovery occurs over time. This study shows that amnesia from ECS in rats gradually resolves within days, indicating time-dependent memory recovery.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Clinical research of multisystem inflammatory syndrome in children].

    Zhonghua er ke za zhi = Chinese journal of pediatrics·2023
    Same author

    [The association study of <i>WWP2</i> gene polymorphisms with delayed encephalopathy after acute carbon monoxide poisoning].

    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2020
    Same author

    Improved RANKL production by memory B cells: A way for B cells promote alveolar bone destruction during periodontitis.

    International immunopharmacology·2018
    Same author

    CD8<sup>+</sup> Foxp3<sup>+</sup> T Cells Affect Alveolar Bone Homeostasis via Modulating Tregs/Th17 During Induced Periodontitis: an Adoptive Transfer Experiment.

    Inflammation·2018
    Same author

    14-3-3 eta depletion sensitizes glioblastoma cells to irradiation due to enhanced mitotic cell death.

    Cancer gene therapy·2014
    Same author

    Ego identity status and values among high school females.

    Journal of youth and adolescence·2013

    Area of Science:

    • Neuroscience
    • Behavioral Neuroscience
    • Cognitive Psychology

    Background:

    • Electroconvulsive shock (ECS) is known to induce temporary memory impairment (amnesia).
    • Understanding the time course of memory recovery after ECS is crucial for both clinical and research applications.
    • Previous studies have explored ECS-induced amnesia, but the temporal dynamics of recovery require further investigation.

    Purpose of the Study:

    • To investigate the time-dependent nature of memory recovery following ECS-induced amnesia in a rodent model.
    • To determine if the behavioral effects of ECS diminish over time.
    • To explore the impact of ECS on the stability of learned performance.

    Main Methods:

    • Forty-four hooded rats were trained on a lever-pressing task for food reward.
    • Following training, rats received either ECS or sham ECS (SECS) after the first lever press.
    • Animals were tested for memory retention during a 10-minute extinction session at either 1 or 3 days post-treatment, measuring latency to respond and response rate.

    Main Results:

    • Rats receiving ECS showed shorter latencies to respond during extinction compared to SECS controls at both 1 and 3 days post-treatment.
    • One day after treatment, ECS rats exhibited a higher response rate during extinction than SECS rats.
    • By 3 days post-treatment, no significant difference in extinction response rate was observed between ECS and SECS groups, suggesting recovery.

    Conclusions:

    • Time-dependent recovery from ECS-induced amnesia can be demonstrated using response rate as a measure in an operant conditioning paradigm.
    • The findings suggest that ECS not only causes amnesia but may also reduce the stability of learned performance.
    • Recovery from ECS-induced memory deficits occurs gradually over a period of days.

    Related Experiment Videos