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Updated: Aug 15, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
[Biocybernetic tests on the identification and mathematical modelling of the motor regulation system and its
Abstract:
By means of the biocybernetically conceived step and impulse loads on the forearm the motor postural regulation of healthy test persons and neurological patients with rigor, spasticity and flaccid pareses of slight degree, respectively, were examined. The analysis of the forms of the transient processes rendered possible a significant differentiation of the groups of test persons and patients. With the help of the mathematical mode the response curves of healthy test persons as well as of patients could be simulated with sufficient exactness. Apart from the step and impulse loads psendorandom binary series of test signals are particularly suitable for the analysis of the motor postural regulation.

