Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Invasive bladder carcinoma managed by irradiation and surgery

J H DeWeerd, M Y Colby, J W Segura

    Urology
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Carcinoma in Situ of the Bladder.

    Cancer·2018
    Same author

    Ureteroscopic treatment of upper tract urinary calculi.

    Minerva urologica e nefrologica = The Italian journal of urology and nephrology·2005
    Same author

    Endourological management of upper tract transitional cell carcinoma.

    BJU international·2003
    Same author

    Long-term results of treatment for ureteroenteric strictures.

    Urology·2001
    Same author

    Is nephroureterectomy necessary in all cases of upper tract transitional cell carcinoma? Long-term results of conservative endourologic management of upper tract transitional cell carcinoma in individuals with a normal contralateral kidney.

    Urology·2001
    Same author

    Current evaluation and management of renal and ureteral stones.

    Saudi medical journal·2001
    Same journal

    Editorial Comment on "A Histopathologic Assessment of Prostate Ductal Anatomy in Relation to Micro-Ultrasound".

    Urology·2026
    Same journal

    Same-Day Discharge Following Multiport Robot-Assisted Simple Prostatectomy: A Prospective Feasibility Study of Outcomes, Costs, and Post-Discharge Healthcare Utilization.

    Urology·2026
    Same journal

    Extended versus Standard Lymph Node Dissection at the Time of Radical Cystectomy for Bladder Cancer.

    Urology·2026
    Same journal

    Intractable Epistaxis and Severe Hypertension in a Young Woman.

    Urology·2026
    Same journal

    A 53-Year-Old Man with Elevated PSA and a Cystic Pelvic Lesion.

    Urology·2026
    Same journal

    Low-Grade, Papillary Bladder Tumors A plea for in-office fulguration.

    Urology·2026
    See all related articles

    Preoperative irradiation and surgery for invasive bladder cancer showed improved survival for patients with no residual disease or low-stage cancer. High-stage cancer patients had significantly lower survival rates, indicating a need for new treatments.

    Area of Science:

    • Urology
    • Oncology
    • Surgical Oncology

    Background:

    • Invasive bladder cancer presents a significant treatment challenge.
    • Optimizing treatment strategies for bladder carcinoma is crucial for patient outcomes.

    Purpose of the Study:

    • To evaluate the survival rates of patients with invasive bladder carcinoma treated with preoperative irradiation and surgical extirpation.
    • To assess the impact of residual disease and cancer stage on long-term survival.

    Main Methods:

    • A nonrandomized study included 444 patients with invasive vesical carcinoma.
    • 416 patients were available for a two-year statistical study after preoperative irradiation and surgery.
    • Survival rates were calculated based on pathologic findings, specifically residual carcinoma and cancer staging.

    Related Experiment Videos

    Main Results:

    • Five-year survival was 66% for patients with no residual carcinoma.
    • Patients with low-stage carcinoma achieved a 71% five-year survival rate.
    • Conversely, patients with high-stage carcinoma had a significantly lower five-year survival rate of 31%.

    Conclusions:

    • Preoperative irradiation and surgery demonstrate efficacy in select bladder cancer patients.
    • Cancer staging is a critical determinant of survival following this treatment regimen.
    • The poor outcomes in high-stage disease highlight the urgent need for novel adjuvant therapies.