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Published on: April 3, 2016
Summary
Collie eye anomaly (CEA) affects over 60% of UK collies and Shetland sheepdogs. This inherited autosomal recessive trait presents diagnostic challenges due to its varied forms.
Area of Science:
- Veterinary Ophthalmology
- Canine Genetics
Background:
- Collie eye anomaly (CEA) is a common inherited disorder in collies and Shetland sheepdogs.
- Previous studies suggested a genetic basis, but comprehensive incidence data in the UK was lacking.
Purpose of the Study:
- To determine the incidence of CEA in Rough Collies, Smooth Collies, and Shetland Sheepdogs in the UK.
- To confirm the mode of inheritance for CEA.
- To discuss the clinical presentation and diagnostic challenges of CEA.
Main Methods:
- Examination of approximately 2500 dogs over a three-year period.
- Pedigree analysis and test mating to investigate inheritance patterns.
Main Results:
- Overall incidence of CEA was approximately 64% in Rough and Smooth Collies.
- Shetland Sheepdogs showed a higher incidence of 72%.
- Autosomal recessive inheritance was confirmed.
Conclusions:
- CEA is highly prevalent in these breeds in the UK.
- The disease is inherited as an autosomal recessive trait.
- Pleomorphism and diagnostic difficulties are significant considerations.
