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[Combined allergy against hazel pollen and hazel nuts]
Summary
Hazel pollen allergy often indicates a sensitization to hazelnuts, detectable through skin tests and RAST. This cross-reactivity highlights a link between pollen and nut allergies.
Area of Science:
- Allergy and Immunology
- Clinical Medicine
- Immunopathology
Context:
- Investigated 225 patients with suspected hazel pollen allergy.
- Utilized cutaneous tests and Radioallergosorbent Test (RAST) for diagnosis.
- Assessed the prevalence and clinical relevance of hazelnut sensitization.
Purpose:
- To determine the relationship between hazel pollen allergy and hazelnut sensitization.
- To identify clinical factors associated with manifest hazelnut allergy.
- To explore cross-reactivity with other allergenic pollens and foods.
Summary:
- 92% of patients showed sensitization to hazelnuts via scratch tests.
- Manifest hazelnut allergy was linked to polyvalent sensitization and early pollinosis onset (Feb/Mar).
- An antigenic relationship between hazel pollen and hazelnut was confirmed.
Impact:
- Suggests a significant cross-reactivity between hazel pollen and hazelnut.
- Identifies specific patient groups at higher risk for manifest hazelnut allergy.
- Reveals frequent co-allergies to related pollens (birch, oak) and certain fruits/vegetables.