Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Left ventricular systolic and diastolic function in hyperthyroidism

M J Friedman, R D Okada, G A Ewy

    American Heart Journal
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Orthopedic Problems in Pregnancy.

    The Physician and sportsmedicine·2016
    Same author

    Beta-Blockade and Response to Exercise: Influence of Training.

    The Physician and sportsmedicine·2016
    Same author

    The use of electrosurgery for arthroscopic subcutaneous lateral release.

    Orthopedics·2014
    Same author

    Operative arthroscopy for the treatment of problems of the medial compartment of the knee.

    Orthopedics·2014
    Same author

    Rationale for continuous chest compression cardiopulmonary resuscitation.

    Heart (British Cardiac Society)·2009
    Same author

    Neuroendocrine properties of intrinsic cardiac adrenergic cells in fetal rat heart.

    American journal of physiology. Heart and circulatory physiology·2004
    Same journal

    Efficacy and safety of human albumin combined with furosemide in acute decompensated heart failure with hepatic dysfunction.

    American heart journal·2026
    Same journal

    International study of Coronary Microvascular Angina (iCorMicA): a registry-based diagnostic study and nested randomized trial.

    American heart journal·2026
    Same journal

    Stratified Medicine with Eplerenone for Myocardial Infarction or Injury and No obstructive Coronary Arteries: A Registry-Based Basket Trial.

    American heart journal·2026
    Same journal

    Revised Lipid-Lowering Therapy Guidelines in a Nationally Representative Sample.

    American heart journal·2026
    Same journal

    Cardiometabolic Health of Low- and Higher-Income Adults in the United States, 2009-2023.

    American heart journal·2026
    Same journal

    Moving Beyond Technical Capability to Regulatory Integration for Digital Health Technology Devices-Brief Communication from the Cardiovascular Sciences Research Consortium.

    American heart journal·2026
    See all related articles

    Hyperthyroidism enhances systolic function and diastolic relaxation of the left ventricle. This study observed increased shortening and lengthening velocities in hyperthyroid patients compared to euthyroid states.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Medical Imaging

    Background:

    • Hyperthyroidism is a condition characterized by excessive thyroid hormone production.
    • Thyroid hormones significantly influence cardiovascular function, affecting heart rate, contractility, and relaxation.
    • The precise impact of hyperthyroidism on left ventricular systolic and diastolic function requires detailed assessment.

    Purpose of the Study:

    • To evaluate the effects of hyperthyroidism on the systolic and diastolic performance of the left ventricle.
    • To compare cardiac function in hyperthyroid patients with their own euthyroid state post-treatment.

    Main Methods:

    • Utilized M-mode echocardiography and systolic time intervals in 13 hyperthyroid patients.
    • Digitally analyzed echocardiographic tracings to determine normalized maximum velocity of shortening and lengthening.

    Related Experiment Videos

  • Measured preejection period index and preejection period/left ventricular ejection time ratio.

    • Main Results:

    • Left ventricular minor axis fractional shortening and normalized maximum velocity of shortening were significantly increased in the hyperthyroid state.
    • Normalized maximum velocity of lengthening, indicating diastolic function, was also elevated during hyperthyroidism.
    • Preejection period index and preejection period/left ventricular ejection time ratio were reduced in hyperthyroid patients.

    Conclusions:

    • Hyperthyroidism leads to an enhanced inotropic state of the left ventricle.
    • Increased diastolic relaxation velocities of the left ventricle are observed in hyperthyroid individuals.
    • These findings highlight significant alterations in cardiac mechanics due to excessive thyroid hormone levels.