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Surgical Induction of Endolymphatic Hydrops by Obliteration of the Endolymphatic Duct
Published on: January 22, 2010
Classification of endolymphatic hydrops
Insights
Endolymphatic hydrops, a condition causing hearing loss and vertigo, is the common pathology behind Ménière's disease and related disorders. This study classifies hydrops into symptomatic and asymptomatic forms, further divided by cause.
Area of Science:
- Otolaryngology
- Pathology
- Neurology
Background:
- Ménière's disease is a disorder characterized by endolymphatic hydrops.
- Endolymphatic hydrops is a common pathophysiologic substrate for a group of related disorders.
Purpose of the Study:
- To evaluate clinical cases and temporal bone specimens to understand endolymphatic hydrops.
- To present a logical classification of endolymphatic hydrops based on clinical data.
- To redefine Ménière's disease within this classification.
Main Methods:
- Clinical case evaluation.
- Temporal bone specimen analysis.
- Development of a classification system for endolymphatic hydrops.
Main Results:
- Endolymphatic hydrops is a pathological condition resulting from various otologic insults.
- A classification distinguishing symptomatic (fluctuating hearing loss, episodic vertigo) and asymptomatic forms is proposed.
- Forms are subclassified into embryopathic, acquired, and idiopathic types.
Conclusions:
- Endolymphatic hydrops is the final common manifestation of diverse otologic insults.
- Ménière's disease is redefined as a specific type of endolymphatic hydrops: idiopathic and symptomatic.
- The classification provides a framework for understanding disorders associated with endolymphatic hydrops.
Abstract:
Ménière's disease is but one member of a family of disorders linked by the common pathophysiologic substrate of endolymphatic hydrops. The authors evaluated both clinical cases and temporal bone specimens and conclude that endolymphatic hydrops is a pathologic condition that is the final common manifestation of a variety of otologic insults. They present a logical classification which, on the basis of clinical data, distinguishes symptomatic and asymptomatic forms. The hallmarks of the symptomatic form are fluctuating hearing loss and episodic vertigo. The asymptomatic form is clinically silent. Each form may be further subclassified into embryopathic, acquired, and idiopathic types. The embryopathic type comprises those cases in which a noxious influence disrupts labyrinthine development in utero. The acquired type includes those cases in which a documented insult, either inflammatory or traumatic, is suffered by a previously normal labyrinth. The idiopathic type encompasses all those cases in which the event precipitating the endolymphatic hydrops is unknown. Ménière's disease is redefined as idiopathic, symptomatic endolymphatic hydrops.
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