[Biological activity of lysozymes of various origins]

The in vitro and in vivo studies showed that lysozymes obtained from O. papillipes, O moubata, A. lahorensis and H. asiaticum had bacteriostatic and bactericidal effects. The effect of the lysozymes obtained from the above ticks was studied in comparison to that of the egg lysozyme. Micrococci, staphylococci, streptococci, E. coli and C. diphtheriae proved to be the most sensitive. Salmonella, Listeria, Pasteurella pseudotuberculosis and Pasteurella tularensis were less sensitive. The comparison of the antibacterial effects of the lysozymes obtained from the ticks and the egg lysozyme showed that the lysozyme from O. moubata, O. papillipes and A. lahorensis had the most pronounced bactericidal effect. The lysozyme obtained from H. asiaticum had the lowest bactericidal activity.