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Related Experiment Videos

Control of polydipsic drinking by a taste aversion procedure

J C Clarke, R F Westbrook

    Pharmacology, Biochemistry, and Behavior
    |September 1, 1978
    PubMed
    Summary
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    Schedule-induced polydipsia in rats, a condition of excessive water intake, was studied. Results suggest common incentive mechanisms drive both normal and excessive drinking behaviors.

    Area of Science:

    • Behavioral Neuroscience
    • Animal Behavior Studies

    Background:

    • Schedule-induced polydipsia is characterized by excessive fluid consumption.
    • Previous research suggested distinct neural systems for normal and polydipsic drinking.

    Purpose of the Study:

    • To investigate the underlying incentive mechanisms of schedule-induced polydipsia.
    • To compare the factors influencing normal versus excessive drinking in rats.

    Main Methods:

    • Rats were subjected to a schedule inducing polydipsia with saccharin-flavored water.
    • Taste aversion was conditioned using lithium chloride after fluid consumption.
    • Drinking behavior was monitored in both experimental and home cage settings.

    Main Results:

    Related Experiment Videos

  • Conditioning a taste aversion to saccharin significantly reduced polydipsic drinking.
  • Recovery of saccharin intake was observed over time post-aversion conditioning.
  • Poisoning after home cage consumption also reduced polydipsic drinking.

    • Conclusions:

    • Common incentive mechanisms appear to regulate both normal and schedule-induced polydipsic drinking.
    • Findings contrast with prior research suggesting separate brain systems for these behaviors.