Therapeutic abortion in late first trimester. Prostaglandin pretreatment compared with primary surgery

One hundred randomly selected nulliparous women, 10-11 weeks pregnant, were submitted to either primary surgery (50 cases) or pretreatment overnight with vaginal suppositories of 15(S)15 methyl prostaglandin F2 alpha methyl ester (50 cases) followed by vacuum aspiration. No peroperative complications were recorded in either of the two groups. Thirtyfive of the 50 pretreated women aborted during the pretreatment period and a variable cervical dilatation was observed in the remaining 15 women of this group. The incidence of early postoperative pelvic infection tended to be less in the pretreated group as compared with the other group.