[Enhanced growth of transplanted tumor in appendectomized rats]

The effect of appendectomy on carcinoma RS-1 growth has been studied in young and old Wistar rats and in randombred ones. It has been found that the tumor grew more intensely in the appendectomized animals. This effect was evident in the young animals, both linear and randombred ones. It remained unchanged after administration of the retinoids (all-transmethylretinoate and retinoid C15) but did not develop in the old animals.