The results of reflux prevention in adults with reflux nephropathy

Twenty adult patients with varying degrees of reflux nephropathy and renal impairment were selected for anti-reflux surgery. Following reflux prevention, those patients with symptoms related to recurrent urinary tract infection were greatly improved. However, in those patients with impaired and deteriorating renal function, surgery only occasionally influences this progression. These patients all had significant proteinuria both pre- and post-operatively. Proteinuria appears to be a more significant prognostic indication of renal deterioration than the degree of reflux or reflux nephropathy.