Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

High risk groups and screening for cancer

O M Jensen

    Cancer Detection and Prevention
    |January 1, 1982
    PubMed
    Summary

    Selective cancer screening shows promise for breast and cervical cancers. However, identifying high-risk individuals using known factors has been challenging, with many cases occurring in low-risk populations.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Soft-tissue sarcoma of the thigh: surgical margin influences local recurrence but not survival in 152 patients.

    Acta orthopaedica Scandinavica·2001
    Same author

    Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations.

    British journal of cancer·2001
    Same author

    [Agressive fibromatosis].

    Ugeskrift for laeger·2001
    Same author

    [Prognostic factors in soft tissue sarcomas. Experiences from the Sarcoma Center in Aarhus].

    Ugeskrift for laeger·2000
    Same author

    Prognostic factors in soft tissue sarcomas: the Aarhus experience.

    European journal of cancer (Oxford, England : 1990)·1999
    Same author

    Objective assessment of photoreceptor displacement and metamorphopsia: a study of macular holes.

    Archives of ophthalmology (Chicago, Ill. : 1960)·1998

    Area of Science:

    • Oncology
    • Preventive Medicine
    • Public Health

    Background:

    • Selective cancer screening aims to reduce morbidity and mortality for breast and cervical cancers.
    • Known risk factors for breast and cervical cancers have not effectively identified high-risk groups for screening.
    • Current mass screening programs identify a significant number of cancer cases in individuals considered low-risk.

    Purpose of the Study:

    • To evaluate the effectiveness of using known risk factors for selective cancer screening.
    • To explore alternative strategies for individualizing cancer screening protocols.
    • To determine the utility of age as a primary screening selection criterion.

    Main Methods:

    • Review of evidence on the benefits of cancer screening for breast and cervix uteri.
    • Analysis of the limitations of using known risk factors in selective screening programs.
    • Examination of data from existing mass screening programs regarding case distribution in risk groups.

    Main Results:

    • Evidence supports the benefits of screening in reducing breast and cervical cancer morbidity and mortality.
    • Utilizing known risk factors for selective screening has yielded disappointing results.
    • Age remains the most reliable characteristic for selecting individuals for screening.
    • A substantial proportion of cancers are detected in individuals categorized as low-risk.

    Conclusions:

    • Selective screening for breast and cervical cancers based on known risk factors is currently ineffective.
    • Age is the only established characteristic for effective screenee selection.
    • Future screening strategies should incorporate identifying risk factors within unselective programs to personalize screening intervals.

    Related Experiment Videos