Related Experiment Videos
Alclometasone dipropionate in psoriasis: a clinical study
The Journal of International Medical Research
|January 1, 1982
Summary
Alclometasone cream and clobetasone butyrate cream showed similar effectiveness in treating psoriasis symptoms like redness and scaling over 21 days. Both topical corticosteroids were well-tolerated, with no reported adverse effects in patients.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Topical corticosteroids are a common treatment for psoriasis.
Purpose of the Study:
- To compare the efficacy and safety of alclometasone cream 0.05% and clobetasone butyrate cream 0.5% in treating psoriasis.
Main Methods:
- A parallel group design with a blind evaluator was used.
- Thirty-one patients with psoriasis were treated twice daily for 21 days.
- Clinical signs (erythema, induration, scaling) and physician's global evaluation were assessed.
Main Results:
- Both alclometasone and clobetasone demonstrated comparable beneficial effects on psoriasis clinical signs.
- No adverse experiences were reported during the study period.
- Physician's global evaluation indicated similar overall improvement for both treatments.
Conclusions:
- Alclometasone cream 0.05% and clobetasone butyrate cream 0.5% exhibit comparable efficacy and safety profiles for psoriasis treatment.
- These topical corticosteroids offer effective management of psoriasis symptoms with good tolerability.