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Tranquillizer use in middle-aged British men

R O Cummins, D G Cook, R C Hume

    The Journal of the Royal College of General Practitioners
    |December 1, 1982
    PubMed
    Summary
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    Tranquillizer use in middle-aged men is linked to physical disease, not age, social class, or smoking. Heavy drinkers showed lower tranquillizer use, suggesting potential substitution for some individuals.

    Area of Science:

    • Epidemiology
    • Pharmacology

    Background:

    • Tranquillizer use is prevalent in middle-aged populations.
    • Understanding factors influencing prescription medication use is crucial for public health.

    Purpose of the Study:

    • To investigate the prevalence and correlates of tranquillizer use among middle-aged men.
    • To examine the association between tranquillizer use and physical disease, lifestyle factors, and demographics.

    Main Methods:

    • Prospective cohort study involving 7,735 middle-aged men.
    • Data collected on tranquillizer usage, diagnosed physical conditions, alcohol consumption, and smoking habits.

    Main Results:

    • 8% of men reported tranquillizer use.
    • Tranquillizer use was associated with diagnosed physical diseases, particularly ischemic heart disease and hypertension.

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  • Older age and non-manual social class showed slightly higher prevalence.
  • Heavy alcohol consumption was inversely associated with tranquillizer use; no association with smoking.

    • Conclusions:

    • Tranquillizer use in this cohort is primarily associated with the presence of diagnosed physical disease, rather than age, social class, or smoking.
    • The inverse relationship with alcohol suggests potential substitution, possibly influenced by awareness of adverse drug interactions.