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Anticholinergic poisoning

L Goldfrank, N Flomenbaum, N Lewin

    Journal of Toxicology. Clinical Toxicology
    |March 1, 1982
    PubMed
    Summary
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    Patients in New York City experienced anticholinergic toxicity from poisoned alcoholic beverages. Investigations suggest deliberate poisoning using scopolamine eyedrops.

    Area of Science:

    • Toxicology
    • Pharmacology
    • Public Health

    Background:

    • Poisoning incidents involving alcoholic beverages have been reported.
    • Anticholinergic toxicity presents a significant public health concern.

    Observation:

    • Numerous patients presented to emergency departments in New York City with anticholinergic toxicity.
    • The onset of symptoms followed the consumption of alcoholic beverages.

    Findings:

    • Analysis of case histories, clinical presentations, and laboratory data indicates a pattern of poisoning.
    • Scopolamine eyedrops were identified as the likely agent used deliberately for poisoning.

    Implications:

    • This highlights a novel method of intentional poisoning with readily available substances.

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  • Public health awareness and emergency response protocols may need to be updated to address this threat.
  • Further research into the source and distribution of the scopolamine eyedrops is warranted.