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Hepatic hemangioendotheliomas and hyperbilirubinemia
Southern Medical Journal
|November 1, 1978
Summary
Jaundice in infants with liver hemangioendotheliomas occurs in 10% of cases. Early diagnosis via liver scan is crucial for infants with hepatomegaly and jaundice, especially with other symptoms.
Area of Science:
- Pediatric Gastroenterology
- Hepatology
- Neonatal Medicine
Background:
- Hepatic hemangioendotheliomas are rare vascular tumors in infants.
- Hyperbilirubinemia and hepatomegaly are significant clinical signs in neonates.
Observation:
- A 3-week-old infant presented with hyperbilirubinemia and hepatomegaly due to liver hemangioendotheliomas.
- Literature review identified jaundice in 10% of infants with hepatic vascular tumors.
Findings:
- Jaundice associated with hepatic vascular tumors occurs in 10% of affected infants.
- Clinical indicators include hepatomegaly, jaundice, gastrointestinal issues, skin hemangiomas, heart failure, or abdominal bruit.
Implications:
- Hepatic hemangioendotheliomas should be considered in the differential diagnosis of neonatal jaundice and hepatomegaly.
- Liver scans are recommended for early detection of these vascular tumors.
- Prompt diagnosis and treatment may improve outcomes for jaundiced infants with these tumors.