Asplenia associated with a congenital diaphragmatic defect and neurologic anomalies

A case of asplenia with the assoicated congential defects of a diaphragmatic hernia, hydrocephalus, anophthalmia, and dysostosis of the frontal skull bones is reported. A small ventricular septal defect was also present. The case is discussed with particular emphasis on the embryologic malformations.