Effect of molybdate on androgen receptor levels in canine prostate

A comparative study on the stabilizing effect of sodium molybdate on androgen receptors was performed using canine prostates. Prostates from intact male dogs of mixed breeds were run in parallel sucrose density gradient analyses, using buffer systems with or without molybdate. Prostates that were homogenized in a molybdate buffer showed a significant increase in androgen receptor content relative to those in a molybdate-free system.