Related Experiment Video
Updated: Aug 16, 2026

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
Published on: November 2, 2019
Lymphoedema following ilio-inguinal lymph node dissection
Abstract:
The results of 90 consecutive cases of ilio-in guinal lymph node dissection have reviewed, with special regard to healing complications and the development of postoperative lymphoedema. An overall healing complication rate of 54.5% was found with reported postoperative oedema in 55.5% of cases. The 37 patients still alive at the time of the study were all examined at a special review clinic. 80% of these patients who had had healing complications developed postoperative oedema, whilst 42% of them with no healing complications developed postoperative oedema. On examination 30% had severe oedema, 50% detectable oedema, and 20% no oedema. The oedema, if it had appeared, developed early postoperatively and was worst in the first 6 months. It gradually improved, but persisted despite time and treatment. The only conservative treatment which appeared to help was the use of elastic support bandage. One-quarter of the patients found mobility was affected to some degree. Good correlation was found between the measurement of the circumference of the leg with a tape measure and the volume of the leg measured by the water displacement method and it would seem that the simplest methods suffice in detecting the oedema.
Related Concept Videos
Lymphatic Vessels and Lymph Transport
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
Development of the Lymphatic System
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:

