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Updated: Apr 5, 2026

3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation
Published on: October 7, 2015
Joint cartilage formation induced by silastic sheet spacer
Abstract:
In an experimental study in rabbits the effect on articular cartilage regeneration from subchondral bone induced by a temporary interposed silicone rubber sheet has been analyzed. The normal articular cartilage of the medial condyle of the femur was resected and the subchondral bone surface covered by a 2 mm thick Silastic sheet which was removed after 2 months. At that time cartilaginous tissue of a hyalin appearance was found to cover the resected surface. As early as one month after removal of the sheet this cartilage showed obvious signs of degeneration and a few months later no regenerating cartilage was left. It is concluded that in this study there is no experimental evidence supporting the idea that temporary interposition of a silicone rubber sheet is beneficial in the treatment of degenerative arthritis.
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