[Effect of various serum fractions on L-cell differentiation]

It has been shown that the accumulation of lipids and maturation of L strain cells into mature lypocytes can be stimulated by high doses (30-60 mg/ml) of serum albumins, egg albumin lysozyme, and gelatin, or with low doses (200-600 mcg/ml) of serum globulins. The globulins are believed to induce differentiation of the L cell on depressing their proliferation. On the contrary, the low doses of albumins stimulate cell division without inducing differentiation.