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Updated: Aug 5, 2026

Urinary Bladder Distention Evoked Visceromotor Responses as a Model for Bladder Pain in Mice
Published on: April 27, 2014
Experimental study on bladder wall's strain in vesical function
Abstract:
The literature is reviewed and the applicability of Laplace's law to the urinary bladder considered as a sphere is critically discussed. Experiments were performed on live rabbits, on isolated bladders and on rubber balloons to study vesical adaptation and response to filling. From the data obtained, the authors propose "strain", rather than tension, as a characteristic quantity of bladder function and indicate the possible application of these experimental results clinically.
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