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Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice
Published on: July 4, 2018
[The expiratory second capacity of the nose--a new method to check the intranasal provocation test]
Abstract:
There are several methods presently in use serving to check the result of the intranasal provocation test. There are simple procedures such as rhinoscopy and cotton swabs as well as technically more cumbersome ones, such as rhinomanumetry. The FEV1 of the nose is a simple method used to evaluate the intranasal provocation test. The results obtained after allergy exposition are objective and reliable. This technique is equally as good as the above mentioned ones, and is not as expensive.
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One key metric is the Inspiratory Capacity (IC), which represents the maximum amount of air that can be inhaled with full effort. IC is calculated by summing the tidal volume and inspiratory reserve volume, typically ranging from 2.4 to 3.6 liters.
The Functional Residual Capacity (FRC) represents the air in the...
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Equipment Required

