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Related Concept Videos

Formation of Dilute Urine01:20

Formation of Dilute Urine

The formation of dilute urine is a critical renal adaptation that maintains fluid balance, particularly during periods of high fluid intake. This process primarily involves the juxtamedullary nephrons. By adjusting the permeability of water and ions in response to physiological conditions, the kidneys can either conserve or excrete water, resulting in concentrated or dilute urine.
Filtrate Osmolarity in the PCT
Initially, as the filtrate passes through the proximal convoluted tubule (PCT), its...
Ureters01:22

Ureters

The ureters are retroperitoneal tubes located on either side of the vertebral column. They are responsible for transporting urine from each kidney to the urinary bladder. These tubes have thick walls and are approximately 25-30 cm long. Their diameter is around 10 mm at the renal pelvis, gradually narrowing to 1 mm as the ureter obliquely enters the posterior bladder wall through the ureteric orifices. The shape of these orifices is slit-like, which helps to prevent urine backflow toward the...
Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant01:25

Drug Dosing in Renal Diseases: Dose Adjustments Based on Drug Clearance and Elimination Rate Constant

In patients with renal disease, dosage adjustments are necessary to maintain therapeutic plasma drug concentrations and prevent toxicity or subtherapeutic exposure. Renal impairment alters drug pharmacokinetics, especially in conditions like uremia, where changes such as prolonged elimination half-life and altered apparent volume of distribution can significantly affect drug disposition. These changes require careful modification of the dosing regimen to achieve the desired clinical...
Anatomy of the Genitourinary System I: Kidneys and Ureters01:11

Anatomy of the Genitourinary System I: Kidneys and Ureters

The upper urinary system comprises two kidneys and two ureters, which are crucial in filtering blood and forming urine.KidneysLocation and Structure:The kidneys are two bean-shaped organs positioned behind the peritoneum on either side of the spine.Kidneys are between the 12th thoracic (T12) and the 3rd lumbar (L3) vertebrae.The position of the liver causes the right kidney to sit slightly lower than the left.Protective Layers:Each kidney is enveloped in a tough, fibrous membrane called the...
Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

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Related Experiment Video

Updated: Jul 11, 2026

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
03:19

Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

Published on: June 21, 2024

Reduction in renal size associated with complete ureteric duplication

M R Funston, H M Du Preez

    Urology
    |October 1, 1978
    PubMed
    Summary

    Ureteric duplication typically increases kidney size. However, this study presents rare cases where non-functioning upper moieties in duplex kidneys led to reduced renal size, challenging typical observations.

    Area of Science:

    • Pediatric Radiology
    • Urology
    • Medical Imaging

    Background:

    • Ureteric duplication is a common congenital anomaly.
    • It is typically associated with normal or enlarged renal size.
    • Non-functioning moieties can occur in duplex systems.

    Observation:

    • Presents two rare cases of duplex kidneys.
    • Both cases feature a non-functioning upper moiety.
    • These kidneys exhibited reduced renal size, contrary to typical findings.

    Findings:

    • Detailed radiologic features of reduced renal size in duplex systems are discussed.
    • The underlying causes for this size reduction are explored.
    • Post-micturition radiography is highlighted for diagnosing urinary tract infections in these cases.

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    A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

    Published on: July 18, 2025

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    Last Updated: Jul 11, 2026

    Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition
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    Point-of-Care Kidney and Genitourinary Ultrasound in Adults: Image Acquisition

    Published on: June 21, 2024

    An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
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    An Immature Murine Model of Reversible Unilateral Ureteral Obstruction

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    A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction
    05:34

    A Mouse Model to Evaluate the Long-Term Structural and Functional Outcomes after the Reversal of Prolonged Unilateral Ureteric Obstruction

    Published on: July 18, 2025

    Implications:

    • Challenges the conventional understanding of renal size in ureteric duplication.
    • Highlights the importance of considering atypical presentations in pediatric urology.
    • Emphasizes the diagnostic value of specific imaging techniques in complex urinary tract anomalies.