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Acquired hypertrichosis lanuginosa
International Journal of Dermatology
|December 1, 1982
Summary
Acquired hypertrichosis lanuginosa, a rare condition causing excessive lanugo hair, is strongly linked to internal cancers. This case highlights its significance as a potential cancer marker.
Area of Science:
- Dermatology
- Oncology
Background:
- Acquired hypertrichosis lanuginosa (AHL) is a rare condition characterized by the sudden onset of lanugo-like hair growth.
- It is often associated with underlying malignancies, making it a crucial diagnostic sign.
Observation:
- A 32-year-old Thai woman presented with generalized lanugo hair, deeply furrowed tongue, and keratosis pilaris.
- She was diagnosed with metastatic adenocarcinoma of the liver.
Findings:
- Literature review identified 24 cases of AHL, with 22 cases linked to confirmed malignancies.
- This strongly suggests AHL is a significant cutaneous indicator of internal cancer.
Implications:
- AHL should prompt a thorough investigation for underlying malignancy.
- Early detection of cancer through cutaneous signs like AHL can improve patient outcomes.