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Abstract:
In this paper, different aspects of gabaergic neurotransmission are considered, with emphasis on gaba neurones distribution in brain as well as various drugs interferences on these neurones. GABA agonists direct or indirect such as respectively muscimol or progabide and benzodiazepines or sodium valproate show anticonvulsant properties. These data support the hypothesis of the gamma aminobutyric acid implication in several neuro-muscular disorders especially in epileptic syndrome.