[Messenger RNA and RNP complexes of normal mouse liver cells and of hepatomas]

The messenger RNA spectra of highly malignant ascites hepatoma 22A and hepatoma 48, belonging to the group of hepatomas with minimum deviations, examined by a sedimentation method in the sacchrose concentration gradient, are characterized by higher heterogenecity as compared with that of the normal liver. The nuclear RNA contents of these hepatomas differ but insignificantly. Whereas in cytoplasm of hepatoma 22A and, to a less extent, of hepatoma 48 some deviations were found in quantitative correlations between polyribosomes and messenger somatic cells (free cytosol particles) in favour of the latter.