[Effect of naloxone on the exploratory activity of mice]

The authors after going carefully over the specific bibliography on the matter, report their results relating to exploratory behaviour in mice after administration of naloxone (0, 05 mg/Kg i.p.). Exploratory behaviour was evaluated using an automatic recording hole-board, that simultaneously registered the locomotor activity. At the utilized doses, naloxone produced a significant decrease of exploring activity and a significant increase of motility, in comparison with drug-naive subjects. At the end, some possible interpretations are proposed about obtained results.