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[Bacteriologic monitoring of external ventricular drainage in children]
Neuro-Chirurgie
|January 1, 1982
Abstract:
The authors report 27 cases of external ventricular drainage employed in children. The usage of this technique caused neither infection nor surinfection in any of the cases. It is difficult to interpret the analysis of the cerebrospinal fluid thus obtained. Decisive criteria for recovery or non infection can be derived by studying the isozymatic profile of the L.D.H. (lactic dehydrogenase).
Insights
External ventricular drainage in children is a safe procedure, showing no infections in 27 cases. Analyzing lactic dehydrogenase (LDH) isozymes offers a reliable method for assessing recovery and infection status.
Area of Science:
- Pediatric Neurosurgery
- Clinical Chemistry
Context:
- External ventricular drainage (EVD) is a common neurosurgical procedure in pediatric patients.
- Assessing infection and recovery post-EVD can be challenging with traditional cerebrospinal fluid (CSF) analysis.
Purpose:
- To evaluate the safety and efficacy of external ventricular drainage in a pediatric cohort.
- To identify reliable biomarkers for determining infection and recovery following EVD.
Summary:
- The study reviewed 27 pediatric cases undergoing external ventricular drainage, with no instances of infection or superinfection reported.
- Cerebrospinal fluid (CSF) analysis proved difficult to interpret for definitive infection criteria.
- Isozymatic profiling of lactic dehydrogenase (LDH) emerged as a decisive method for assessing patient recovery and absence of infection.
Impact:
- This research suggests that EVD is a safe intervention in pediatric neurosurgery.
- The findings highlight the potential of LDH isozyme analysis as a superior diagnostic tool for post-EVD complications, guiding clinical management.