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Thyroid disease in diabetics

D D Sugrue, M McEvoy, M I Drury

    Postgraduate Medical Journal
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Thyroid dysfunction affects 1.1% of diabetic patients, with most cases preceding thyroid disease. Screening diabetic individuals for thyroid issues is valuable, as relapse rates after carbimazole treatment are similar to non-diabetic patients.

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    Area of Science:

    • Endocrinology
    • Metabolic Diseases
    • Thyroidology

    Background:

    • Diabetes mellitus and thyroid dysfunction are common endocrine disorders.
    • Concurrent thyroid dysfunction in diabetic patients is a significant clinical concern.
    • Understanding the prevalence and characteristics of thyroid dysfunction in diabetes is crucial for patient management.

    Purpose of the Study:

    • To determine the prevalence of clinical thyroid dysfunction in a diabetic clinic population.
    • To investigate the relationship between diabetes type, disease onset, and thyroid dysfunction.
    • To assess the relapse rates of hyperthyroidism treated with carbimazole in diabetic patients.

    Main Methods:

    • Retrospective analysis of 5,000 patients in a diabetic clinic.

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  • Identification of patients with concurrent clinical thyroid dysfunction (hyperthyroidism and hypothyroidism).
  • Analysis of diabetes type, disease progression, and treatment outcomes for thyroid dysfunction.

    • Main Results:

    • 1.1% (113/5,000) of diabetic patients had concurrent thyroid dysfunction (56 hyperthyroid, 57 hypothyroid).
    • Insulin-dependent diabetes was more common (62.8%) among these patients.
    • Diabetes preceded thyroid disease in 75.2% of cases.
    • Among 20 patients treated with carbimazole for over two years, 75% relapsed, a rate comparable to non-diabetic individuals.

    Conclusions:

    • Clinical thyroid dysfunction is present in a notable percentage of diabetic patients.
    • The sequence of disease onset, with diabetes often preceding thyroid issues, is important.
    • Screening diabetic patients for thyroid dysfunction is clinically relevant.
    • Long-term carbimazole treatment for hyperthyroidism in diabetics shows similar relapse rates to the general population, suggesting standard treatment approaches may be applicable.