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Alcohol-containing pharmaceuticals

W A Parker

    The American Journal of Drug and Alcohol Abuse
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Ethanol and isopropanol are common active ingredients in many U.S. drug products, offering solvent and pharmacological benefits. Clinicians can use a compiled list of nearly 500 alcohol-containing medications to counsel patients avoiding alcohol.

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    Area of Science:

    • Pharmacology
    • Pharmaceutical Sciences

    Background:

    • Ethanol and isopropanol are utilized as active ingredients in diverse prescription and nonprescription drug formulations, including oral, parenteral, and topical applications.
    • Beyond their primary role as solvents for drug solubilization, these alcohols exhibit concentration-dependent pharmacological effects such as sedation, carmination, and antiseptic properties.

    Purpose of the Study:

    • To present a comprehensive compilation of alcohol-containing pharmaceutical products available in the United States.
    • To provide clinicians with a reference to identify medications containing ethanol or isopropanol for patient counseling.

    Main Methods:

    • A systematic compilation of nearly 500 American prescription and nonprescription drug products containing alcohol was created.
    • Data collected included proprietary drug name, manufacturer, alcohol type and concentration, route of administration, and prescription status.

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    Main Results:

    • The compilation identifies numerous drug products containing significant concentrations of ethanol and isopropanol.
    • Oral preparations may contain 40% or more alcohol, potentially leading to substantial daily alcohol consumption by patients.

    Conclusions:

    • A comprehensive list of alcohol-containing drugs is available to assist healthcare professionals.
    • This resource is crucial for advising patients on alcohol-deterrent therapies or those who must avoid alcohol intake.